Brand(s): Galvus Met / Jalra M
Manufacturer: Novartis / USV
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Galvumet is a combined medicine that contains two active components 50mg of vildagliptin and 1000mg of metformin. It is designed for patients with a type 2 diabetes mellitus.
Generic Galvumet is used to treat type 2 diabetes mellitus in people who are already taking vildagliptin and metformin tablets separately, or whose diabetes cannot be controlled by metformin alone.
Generic Galvumet is also used with a sulfonylurea by patients whose blood sugar levels are not adequately controlled when taking only metformin and a sulfonylurea.
Generic Galvumet is also added to insulin in patients when a stable dose of insulin and metformin do not provide adequate blood sugar control.
It is prescribed by your doctor together with diet and exercise.
Generic Galvumet contains two ingredients: vildagliptin, which belongs to a class of medicines called 'islet enhancers', and metformin, which belongs to the 'biguanide' class.
Type 2 diabetes mellitus used to be known as 'non-insulin-dependent diabetes mellitus (NIDDM)' or 'maturity onset diabetes'.
Type 2 diabetes develops if the body does not produce enough insulin, or where the insulin that your body makes does not work as well as it should. It can also develop if the body produces too much glucagon.
Insulin is a substance which helps to lower the level of sugar in your blood, especially after meals. Glucagon is another substance which triggers the production of sugar by the liver, causing the blood sugar to rise. The pancreas makes both of these substances.
Generic Galvumet helps to control the blood sugar level. It works by making the pancreas produce insulin and less glucagon (effect of vildagliptin) and also by helping the body to make better use of the insulin it produces (effect of metformin).
Your doctor will prescribe Generic Galvumet either alone or in combination with another antidiabetic medicine to replace the antidiabetic medicine(s) you are already taking, where that medicine(s) alone is not enough to control your blood sugar level.
It is important that you continue to follow the diet and/or exercise recommended for you whilst you are on treatment with Generic Galvumet.
Ask your doctor if you have any questions about why this medicine has been prescribed for you.
Your doctor may have prescribed it for another reason.
Generic Galvumet is not a substitute for insulin. It is not used to treat type 1 diabetes (where your body does not produce insulin at all), or diabetic ketoacidosis.
This medicine is only available with a doctor's prescription. It is not addictive.
There is not enough information to recommend this medicine for use in children under 18 years old.
Do not take this medicine if you have an allergy to:
Some of the symptoms of an allergic reaction may include shortness of breath; wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
Do not take this medicine if you have any of the following:
Do not take this medicine if you are going to have a contrast x-ray (a type of x-ray involving an injectable dye).
This medicine may affect your kidney function so you will need to stop taking it at the time of the procedure and for a few days after.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.
In that case, return it to your pharmacist.
Discard any other medicines containing metformin that your doctor might have prescribed to you in the past and that you may still have in your possession.
Generic Galvumet contains metformin. If you have more than one metformin-containing medicine in your possession you may accidentally take too much (overdose). Accidentally taking too much metformin can cause a very serious side effect called lactic acidosis.
ACCIDENTAL METFORMIN OVERDOSING IS A SIGNIFICANT SAFETY RISK.
Ask your doctor or pharmacist if you are unsure if you have any other medicines containing metformin.
Metformin is sold under many different brand names in Australia. Your doctor or pharmacist will know which other medicines also contain metformin.
Tell your doctor if you have allergies to any other medicines, foods, dyes or preservatives.
Your doctor will want to know if you are prone to allergies.
Tell your doctor if you are pregnant or intend to become pregnant.
Your doctor will discuss the possible risks and benefits involved.
Tell your doctor if you are breast-feeding or plan to breast-feed.
It is not known if the active ingredient of Generic Galvumet passes into breast milk and could affect your baby.
Tell your doctor if you have any of the following medical conditions:
If you are not sure whether any of the above conditions apply to you, your doctor can advise you.
Your doctor will do some blood and urine tests for sugar level regularly, and for liver and kidney function at the start of treatment and regularly while you are on treatment.
Alcohol, diet, exercise and your general health all strongly affect the control of your diabetes.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
You may need to take different amounts of your medicines or to take different medicines while you are taking Generic Galvumet. Your doctor and pharmacist have more information.
This is particularly important with the following medicines:
If you have not told your doctor about any of these things, tell him/her before you start taking this medicine.
Follow all directions given to you by your doctor and pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the label, ask your doctor or pharmacist for help.
The usual dose of Generic Galvumet is one tablet twice a day. Your doctor will tell you exactly how many tablets to take. Do not exceed two tablets a day.
Your doctor will monitor your blood glucose levels and may increase or decrease the dose of Generic Galvumet to maintain good control of your diabetes.
Swallow Generic Galvumet tablets whole with a glass of water.<
Take your medicine at about the same time each day.
Taking it at the same time each day will have the best effect. It will also help you remember when to take it.
Take this medicine either with or just after food.
This will reduce the chance of you getting an upset stomach.
Continue taking your medicine for as long as your doctor tells you to.
Your doctor will check your progress to make sure the medicine is working and will discuss with you how long your treatment should continue.
Do not stop taking Generic Galvumet unless your doctor tells you to.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose that you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.
Immediately telephone your doctor or Poisons Information Centre (telephone number: 13 11 26), or go to Accident and Emergency at your nearest hospital if you think that you or anyone else may have accidentally taken too much Generic Galvumet. Do this even if there are no signs of discomfort or poisoning. Keep the telephone numbers for these places handy.
You may need urgent medical attention.
Symptoms of an overdose may include:
Symptoms of an overdose can also include the symptoms of lactic acidosis:
If you become pregnant while taking this medicine, tell your doctor immediately.
Generic Galvumet should not be taken if you are pregnant. Insulin is more suitable for controlling blood glucose during pregnancy.
Carefully follow your doctor's and/or dietician's advice on diet, drinking alcohol and exercise.
Keep all of your doctor's appointments so that your progress can be checked.
Your doctor will do regular checks to help prevent you from having side effects from the medicine or developing serious complications of diabetes. These will include tests for:
Make sure you check your blood glucose levels regularly.
This is the best way to tell if your diabetes is being controlled properly. Your doctor or diabetes educator will show you how and when to do this.
Tell your doctor if you become ill or experience extra stress, injury, fever, infection or need surgery.
Your blood glucose may become difficult to control at these times.
Make sure you keep enough medicine to last over weekends and holidays.
It is important to keep your blood glucose controlled at all times to prevent serious complications of diabetes from happening.
Remind your doctor and pharmacist that you are taking Generic Galvumet if you are about to be started on any new medicine.
Tell any other doctor, dentist or pharmacist who treats you that you are taking Generic Galvumet.
Do not give this medicine to anyone else, even if their condition seems similar to yours.
Do not use it to treat any other complaints unless your doctor tells you to.
Be careful driving, operating machinery or doing jobs that require you to be alert until you know how this medicine affects you.
If your blood glucose level becomes too low, you may feel dizzy, lightheaded, weak or tired and your reaction time may be slower than usual. If you have any of these symptoms, do not drive or do anything else that could be dangerous.
Be careful when doing any of the following things, which increase the risk of your blood glucose becoming too low:
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Generic Galvumet even if you do not think it is connected with the medicine.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Do not be alarmed by these lists of possible side effects.
You may not experience any of them.
Ask your doctor, pharmacist or diabetes educator to answer any questions you may have.
Tell your doctor if you notice any of the following side effects and they worry you:
Stop taking Generic Galvumet and tell your doctor immediately or go to Accident and Emergency if you notice any of the following:
Stop taking Generic Galvumet if you get any of the symptoms of lactic acidosis and go to Accident and Emergency immediately.
Metformin has caused lactic acidosis in rare cases. This is a medical emergency that can cause death. It is caused by build-up of lactic acid in your blood. The symptoms of lactic acidosis are:
Tell your doctor if you notice anything else that is making you feel unwell.
Some people may have other side effects not yet known or mentioned in this leaflet. Some side effects (e.g. changes in liver function) can only be found by laboratory testing.
Keep your medicine in the original container until it is time to take it. Store it in a cool dry place where the temperature stays below 30°C. Protect from moisture. Do not store Generic Galvumet or any other medicine in the bathroom or near a sink. Do not leave it in the car or on window sills. Keep the medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any tablets you have left over.